Relief from your knee pain caused by osteoarthritis may be 3 injections away.

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1% sodium hyaluronate is used to help relieve knee pain due to osteoarthritis. It is used for patients who do not get enough relief from simple pain medications, such as acetaminophen, or from exercise and physical therapy.

Osteoarthritis is a condition that involves the wearing down of cartilage (the protective covering on the ends of your bones). In osteoarthritis, there may not be enough, or there may be a decrease in the quality, of the gel‐like substance in the joint and surrounding tissues for the joint to work properly.


Are there any reasons why I should not take 1% sodium hyaluronate?

  • Your doctor will determine if you are an appropriate candidate for 1% sodium hyaluronate.
  • Do not take 1% sodium hyaluronate if you have had previous allergic reactions to 1% sodium hyaluronate or hyaluronan products.
  • 1% sodium hyaluronate should not be injected into the knee if you have a knee joint infection or skin diseases or infections around the injection site.

What should my doctor warn me about?

  • After you receive an injection of 1% sodium hyaluronate, you may experience temporary pain or swelling of the injected joint.
  • 1% sodium hyaluronate has not been tested in pregnant women or women who are nursing. Tell your doctor if you think you are pregnant or nursing a child before agreeing to be injected with 1% sodium hyaluronate.
  • 1% sodium hyaluronate has not been tested in persons less than 21 years of age.

What are some of the possible side effects of 1% sodium hyaluronate?

The following are the most common adverse events that occurred during the clinical trial of 1% sodium hyaluronate:

  • Pain in the knee or at the injection site
  • Swelling and discomfort of the joint

What should I do after receiving a 1% sodium hyaluronate injection?

  • After receiving your injection, limit physical activity. Someone may need to drive you home from the doctor’s office.
  • Avoid strenuous physical activity for 48 hours following the injection to help keep your knee from swelling. Some examples of activities to avoid include: running, tennis, hiking, jumping, swimming, heavy lifting (weight lifting), jogging, bicycling, and aerobic exercise.
  • Do not stand on your feet for more than one hour at a time during the first 48 hours following your injection.
  • You should ask your doctor when you should begin major physical activities again.

When should I call my doctor?

If you experience any of the adverse effects or symptoms described earlier or if you have any other problems, you should call your doctor immediately.

Please read the Patient Information and Directions for Use in the full Prescribing Information.